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06.11.2018
Materials – Coating 07293-01
06.11.2018
Materials – Coating 10581-01
06.11.2018
Chemistry / Environment 08758-01
06.11.2018
11127-01
06.11.2018
Environment and Energy 11107-01
19.10.2018
Medical Diagnostic 08504-01
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02283-01
International Patent application WO2011012779
Nicolas MANO
Claire STINES-CHAUMEIL
Fabien DURAND
Exclusive or non-exclusive licenses and collaborative research.
Centre de recherches Paul Pascal (C.R.P.P) – France
http://www.crpp-bordeaux.cnrs.fr
This application covers soluble PQQ-GDH enzyme mutants designed for glucose monitoring electrodes, especially blood assays for diabetes glucose monitoring and for their use in biofuel cells.
In addition, such mutants are fundamental for understanding the mechanism of glucose oxidation.
Advantages
1- Mutants twice more active than the wild type enzyme for glucose oxidation
2- Easiness of production
3- 20% more selective towards maltose
4- Stable in physiological conditions
Glucose sensors, biofuel cells, any systems requiring the enzymatic oxidation of glucose at high rate.
We already demonstrated the concept and the enzyme is available for testing.
2 papers have been published so far with these mutants and one more paper is under review:
– Durand & al, BBRC, 2010, 402,750; Flexer & al, Anal Chem, 2011, in press
– Durand & al, J. Am Chem Soc, (2011), in press.
For further information, please contact us (Ref 02283-01)
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06.11.2018
Materials – Coating 07293-01
06.11.2018
Materials – Coating 10581-01
06.11.2018
Chemistry / Environment 08758-01
06.11.2018
11127-01
06.11.2018
Environment and Energy 11107-01
19.10.2018
Medical Diagnostic 08504-01