New mutants of glucose oxidase from penicillium amagasakiense
Référence
04461-01
Statut des brevets
French patent application FR1157979 filed on September 08, 2011 and entitled « Mutants de la glucose oxydase de Penicillium Amagasakiense »
Inventeurs
Nicolas Mano
Olivier COURJEAN
Emilie TREMEY
Sébastien GOUNEL
Statut commercial
Exclusive or non exclusive licenses, Research collaboration.
Laboratoire
Centre de recherches Paul Pascal (CRPP, UPR8641), Pessac, France
Description
TECHNICAL DESCRIPTION
This application covers Glucose oxidase mutants designed for glucose monitoring, especially blood assays for diabetes glucose monitoring and for their use in biofuel cells electrodes.
In addition, such mutants are fundamental for understanding the mechanism of glucose oxidation.
ADVANTAGES
We have shown that this new Glucose oxidase presents main advantages compared to previous commercial enzymes especially:
1 Higher Kcat and lower Km than the widely used GOx from Aspergillus niger
2 80 % less sensititive to O2
3 Stable in physiological conditions
INDUSTRIAL APPLICATIONS
Glucose sensors, biofuel cells, any systems requiring the enzymatic oxidation of glucose at high rate without interference of O2.
STATE FO DEVELOPMENT
We already demonstrated the concept in electrochemistry. Samples are available for testing.
Besoin de plus d'informations ?
Nous contacterTechnologies Liées
-
06.11.2018
Glucose biofuel cell pad
Environnement et Energie 11107-01
-
08.02.2017
Method for determining the size distribution of a mixture of particles of (macro)molecules using taylor dispersion and associated system
Chimie, Santé / Thérapeutique, Diagnostic médical, Matériaux – Revêtements 00957-03
-
07.06.2016
Novel recombinant lectins and applications for the detection of pathological state markers
Santé / Thérapeutique, Diagnostic médical 06433-01