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Use of cells derived from adipose tissue for antitumoral treatment

Référence

00611-01

Statut des brevets

French patent application FR0604443 filed on May 18th, 2006 entitled “Utilisation de cellules derives du tissu adipeux pour la preparation d’un medicament anti-tumoral”

Inventeurs

Pierre CORDELIER
Louis BUCAIL
Louis CASTEILLA
Béatrice COUSIN-DELARUE
Jean-Marie PERON

Statut commercial

Exclusive or non-exclusive licenses

Laboratoire

Laboratoire de Neurobiologie, Plasticité Tissulaire et Métabolisme Energétique, a CNRS and University of Toulouse III (UPS) laboratory (UMR 5018) in Toulouse, France.

Description

CONTEXT

This invention reports the use of cells derived from adipose tissue for elaboration of antitumoral treatment, in particular for gastrointestinal cancer. In this type of cancer, the effectiveness of conventional therapeutics, like surgery, chemotherapy and radiotherapy have only limited effect on survival or tumour    load. Unfortunately, actual medical treatment (chemotherapy and radiation) for theses cancer does not result in many cures, and combinations of chemotherapy and radiotherapy are only allowing patients to live longer and have a better quality of life. In this domain there is a lack of effective therapy, especially in advanced cancer when the surgery is not possible any more.

The inventor presents a new alternative by using cellular therapy. Cells from the vascular stroma fraction of extra-medular white adipose tissue, called ADAS (for adipose-derived adult stem cells) are able to slow down the development of tumour.

TECHNICAL DESCRIPTION

This invention reports the use of cells derived from adipose tissue for elaboration of antitumoral treatment, in particular for gastrointestinal cancer. In this type of cancer, the effectiveness of conventional therapeutics, like surgery, chemotherapy and radiotherapy have only limited effect on survival or tumour    load. Unfortunately, actual medical treatment (chemotherapy and radiation) for theses cancer does not result in many cures, and combinations of chemotherapy and radiotherapy are only allowing patients to live longer and have a better quality of life. In this domain there is a lack of effective therapy, especially in advanced cancer when the surgery is not possible any more.

The inventor presents a new alternative by using cellular therapy. Cells from the vascular stroma fraction of extra-medular white adipose tissue, called ADAS (for adipose-derived adult stem cells) are able to slow down the development of tumour.

INDUSTRIAL APPLICATIONS

The application of this invention is the development of a new cancer treatment, in particular for gastrointestinal cancer like Pancreatic Cancer, Gastric Cancer and Colorectal Cancer.

For further information, please contact us (Ref 00611-01)

 


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