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Treatment for eating disorders : 5-HT4 receptors

Reference

85584-01

Patents status

French patent application FR0213725 filed on October 31, 2002 and entitled “Composition pharmaceutique pour la préparation d’un médicament destiné à traiter et/ou prévenir une pathologie liée à une conduite obsessionnelle”

Inventors

Valérie COMPAN

commercial status

Exclusive or non-exclusive licenses and collaborative research.

Laboratory

Centre CNRS-INSERM de Pharmacologie-Endocrinologie (CCIPE, UPR9023), Montpellier, France.

Description

TECHNICAL DESCRIPTION

The invention describes the role of 5-HT4 receptors.
The inventors have performed tests in mice and have shown that inactivation of the 5-HT4 receptors helps to a decrease sensitivity to stress-induced anorexia.

INDUSTRIAL APPLICATIONS

5-HT4 receptor antagonists could be used to treat Anorexia and decrease sensitivity to drug abuse. Moreover, 5-HT4 receptor agonists could be used to treat bulimia and hyperphagia.

 


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