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Spheniscins: peptides with antimicrobial and food preserving properties



Statut des brevets

French patent application FR0208207 filed on July 1st, 2002 and entitled “Peptides ayant des propriétés antimicrobiennes et les compositions les contenant notamment pour la conservation des aliments”


Philippe BULET


Centre d’Ecologie et Physiologie Energétiques, a CNRS (UPR 9010) and Université Louis Pasteur laboratory in Strasbourg, France. Réponse Immunitaire et Développement chez les Insectes, a CNRS (UPR 9022) and Université Louis Pasteur laboratory in Strasbourg, France.


Technical description

This invention describes the identification and the characterization of 2 peptides with antimicrobial activities isolated from the stomach content of the King Penguin (Aptenodytes patagonicus). These peptides, belonging to the ß-defensin family, are strongly suspected to contribute to the notable conservation of food stored in the male King Penguin stomach during the egg incubation period. In vitro tests revealed a marked antimicrobial activity against a broad range of Gram-negative and Gram-positive bacteria as well as fungus.
More generally, this invention refers to the characterization of these new peptides called spheniscins.

Industrial applications

Synthetic or recombinant peptides could be prepared for their use in:
– agri-food, as food preservatives,
– human and animal health, for the prevention and treatment of infectious diseases.

For further information, please contact us (Ref 85437-01)

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